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  2. Hsu YH, Pintacuda G, Liu R, Nacu E, Kim A, Tsafou K, Petrossian N, Crotty W, Suh JM, Riseman J, MartĂ­n JM, Biagini JC, Mena D, Ching JKT, Malolepsza E, Li T, Singh T, Ge T, Egri SB, Tanenbaum B, Stanclift CR, Apffel AM, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Stanley Global Asia Initiatives, Carr SA, Schenone M, Jaffe J, Fornelos N, Huang H, Eggan KC, Lage K (2023) ‘Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.’ iScience, 26 (5): 106701. PMID: 37207277
  3. Pintacuda G, Hsu YH, Tsafou K, Li KW, MartĂ­n JM, Riseman J, Biagini JC, Ching JKT, Mena D, Gonzalez-Lozano MA, Egri SB, Jaffe J, Smit AB, Fornelos N, Eggan KC, Lage K (2023) ‘Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.’ Cell Genom, 3 (3): 100250. PMID: 36950384
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  7. Pintacuda G, Lassen FH, Hsu YH, Kim A, MartĂ­n JM, Malolepsza E, Lim JK, Fornelos N, Eggan KC, Lage K (2021) ‘Genoppi is an open-source software platform for robust and standardized integration of proteomic and genetic data.’ Nat Commun, 12 (1): 2580. PMID: 33972534
  8. Roux B, Vaganay C, Vargas JD, Alexe G, Benaksas C, Pardieu B, Fenouille N, Ellegast JM, Malolepsza E, Ling F, Sodaro G, Ross L, Pikman Y, Conway AS, Tang Y, Wu T, Anderson DJ, Le Moigne R, Zhou HJ, Luciano F, Hartigan CR, Galinsky I, DeAngelo DJ, Stone RM, Auberger P, Schenone M, Carr SA, Guirouilh-Barbat J, Lopez B, Khaled M, Lage K, Hermine O, Hemann MT, Puissant A, Stegmaier K, Benajiba L (2021) ‘Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor.’ Sci Transl Med, 13 (587): eabg1168. PMID: 33790022
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  12. Iqbal S, PĂ©rez-Palma E, Jespersen JB, May P, Hoksza D, Heyne HO, Ahmed SS, Rifat ZT, Rahman MS, Lage K, Palotie A, Cottrell JR, Wagner FF, Daly MJ, Campbell AJ, Lal D (2020) ‘Comprehensive characterization of amino acid positions in protein structures reveals molecular effect of missense variants.’ Proc Natl Acad Sci U S A, 117 (45): 28201-28211. PMID: 33106425
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  40. Rondas D, Bugliani M, D’Hertog W, Lage K, Masini M, Waelkens E, Marchetti P, Mathieu C, Overbergh L (2013) ‘Glucagon-like peptide-1 protects human islets against cytokine-mediated ÎČ-cell dysfunction and death: a proteomic study of the pathways involved.’ J Proteome Res, 12 (9): 4193-206. PMID: 23937086
  41. Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, Medland SE, Todt U, McArdle WL, Quaye L, Koiranen M, Ikram MA, LehtimĂ€ki T, Stam AH, Ligthart L, Wedenoja J, Dunham I, Neale BM, Palta P, Hamalainen E, SchĂŒrks M, Rose LM, Buring JE, Ridker PM, Steinberg S, Stefansson H, Jakobsson F, Lawlor DA, Evans DM, Ring SM, FĂ€rkkilĂ€ M, Artto V, Kaunisto MA, Freilinger T, Schoenen J, Frants RR, Pelzer N, Weller CM, Zielman R, Heath AC, Madden PAF, Montgomery GW, Martin NG, Borck G, Göbel H, Heinze A, Heinze-Kuhn K, Williams FMK, Hartikainen AL, Pouta A, van den Ende J, Uitterlinden AG, Hofman A, Amin N, Hottenga JJ, Vink JM, HeikkilĂ€ K, Alexander M, Muller-Myhsok B, Schreiber S, Meitinger T, Wichmann HE, Aromaa A, Eriksson JG, Traynor B, Trabzuni D, North American Brain Expression Consortium., UK Brain Expression Consortium., Rossin E, Lage K, Jacobs SBR, Gibbs JR, Birney E, Kaprio J, Penninx BW, Boomsma DI, van Duijn C, Raitakari O, Jarvelin MR, Zwart JA, Cherkas L, Strachan DP, Kubisch C, Ferrari MD, van den Maagdenberg AMJM, Dichgans M, Wessman M, Smith GD, Stefansson K, Daly MJ, Nyholt DR, Chasman D, Palotie A (2013) ‘Genome-wide meta-analysis identifies new susceptibility loci for migraine.’ Nat Genet, 45 (8): 912-917. PMID: 23793025
  42. Pers TH, DworzyƄski P, Thomas CE, Lage K, Brunak S (2013) ‘MetaRanker 2.0: a web server for prioritization of genetic variation data.’ Nucleic Acids Res, 41 (Web Server issue): W104-8. PMID: 23703204
  43. Margolin DH, Kousi M, Chan YM, Lim ET, Schmahmann JD, Hadjivassiliou M, Hall JE, Adam I, Dwyer A, Plummer L, Aldrin SV, O’Rourke J, Kirby A, Lage K, Milunsky A, Milunsky JM, Chan J, Hedley-Whyte ET, Daly MJ, Katsanis N, Seminara SB (2013) ‘Ataxia, dementia, and hypogonadotropism caused by disordered ubiquitination.’ N Engl J Med, 368 (21): 1992-2003. PMID: 23656588
  44. Miraoui H, Dwyer AA, Sykiotis GP, Plummer L, Chung W, Feng B, Beenken A, Clarke J, Pers TH, Dworzynski P, Keefe K, Niedziela M, Raivio T, Crowley WF Jr, Seminara SB, Quinton R, Hughes VA, Kumanov P, Young J, Yialamas MA, Hall JE, Van Vliet G, Chanoine JP, Rubenstein J, Mohammadi M, Tsai PS, Sidis Y, Lage K, Pitteloud N (2013) ‘Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism.’ Am J Hum Genet, 92 (5): 725-43. PMID: 23643382
  45. Longoni M, Lage K, Russell MK, Loscertales M, Abdul-Rahman OA, Baynam G, Bleyl SB, Brady PD, Breckpot J, Chen CP, Devriendt K, Gillessen-Kaesbach G, Grix AW, Rope AF, Shimokawa O, Strauss B, Wieczorek D, Zackai EH, Coletti CM, Maalouf FI, Noonan KM, Park JH, Tracy AA, Lee C, Donahoe PK, Pober BR (2012) ‘Congenital diaphragmatic hernia interval on chromosome 8p23.1 characterized by genetics and protein interaction networks.’ Am J Med Genet A, 158A (12): 3148-58. PMID: 23165946
  46. Lage K, Greenway SC, Rosenfeld JA, Wakimoto H, Gorham JM, SegrĂš AV, Roberts AE, Smoot LB, Pu WT, Pereira AC, Mesquita SM, Tommerup N, Brunak S, Ballif BC, Shaffer LG, Donahoe PK, Daly MJ, Seidman JG, Seidman CE, Larsen LA (2012) ‘Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development.’ Proc Natl Acad Sci U S A, 109 (35): 14035-40. PMID: 22904188
  47. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV (2012) ‘Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.’ Cell Rep, 2 (2): 419-31. PMID: 22902405
  48. Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV (2012) ‘Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.’ Nat Commun, 3: 876. PMID: 22673903
  49. Talkowski ME, Rosenfeld JA, Blumenthal I, Pillalamarri V, Chiang C, Heilbut A, Ernst C, Hanscom C, Rossin E, Lindgren AM, Pereira S, Ruderfer D, Kirby A, Ripke S, Harris DJ, Lee JH, Ha K, Kim HG, Solomon BD, Gropman AL, Lucente D, Sims K, Ohsumi TK, Borowsky ML, Loranger S, Quade B, Lage K, Miles J, Wu BL, Shen Y, Neale B, Shaffer LG, Daly MJ, Morton CC, Gusella JF (2012) ‘Sequencing chromosomal abnormalities reveals neurodevelopmental loci that confer risk across diagnostic boundaries.’ Cell, 149 (3): 525-37. PMID: 22521361
  50. Russell MK, Longoni M, Wells J, Maalouf FI, Tracy AA, Loscertales M, Ackerman KG, Pober BR, Lage K, Bult CJ, Donahoe PK (2012) ‘Congenital diaphragmatic hernia candidate genes derived from embryonic transcriptomes.’ Proc Natl Acad Sci U S A, 109 (8): 2978-83. PMID: 22315423
  51. Ferreira GB, Kleijwegt FS, Waelkens E, Lage K, Nikolic T, Hansen DA, Workman CT, Roep BO, Overbergh L, Mathieu C (2012) ‘Differential protein pathways in 1,25-dihydroxyvitamin d(3) and dexamethasone modulated tolerogenic human dendritic cells.’ J Proteome Res, 11 (2): 941-71. PMID: 22103328
  52. Cotsapas C, Voight BF, Rossin E, Lage K, Neale BM, Wallace C, Abecasis GR, Barrett JC, Behrens T, Cho J, De Jager PL, Elder JT, Graham RR, Gregersen P, Klareskog L, Siminovitch KA, van Heel DA, Wijmenga C, Worthington J, Todd JA, Hafler DA, Rich SS, Daly MJ, Daly MJ (2011) ‘Pervasive sharing of genetic effects in autoimmune disease.’ PLoS Genet, 7 (8): e1002254. PMID: 21852963
  53. Berchtold LA, StĂžrling ZM, Ortis F, Lage K, Bang-Berthelsen C, Bergholdt R, Hald J, Brorsson CA, Eizirik DL, Pociot F, Brunak S, StĂžrling J (2011) ‘Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis.’ Proc Natl Acad Sci U S A, 108 (37): E681-8. PMID: 21705657
  54. Pers TH, Hansen NT, Lage K, Koefoed P, Dworzynski P, Miller ML, Flint TJ, Mellerup E, Dam H, Andreassen OA, Djurovic S, Melle I, BĂžrglum AD, Werge T, Purcell S, Ferreira MA, Kouskoumvekaki I, Workman CT, Hansen T, Mors O, Brunak S (2011) ‘Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes.’ Genet Epidemiol, 35 (5): 318-32. PMID: 21484861
  55. Rossin EJ, Lage K, Raychaudhuri S, Xavier RJ, Tatar D, Benita Y, International Inflammatory Bowel Disease Genetics Constortium., Cotsapas C, Daly MJ (2011) ‘Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.’ PLoS Genet, 7 (1): e1001273. PMID: 21249183
  56. Ferreira GB, Overbergh L, van Etten E, Lage K, D’Hertog W, Hansen DA, Maris M, Moreau Y, Workman CT, Waelkens E, Mathieu C (2008) ‘Protein-induced changes during the maturation process of human dendritic cells: A 2-D DIGE approach.’ Proteomics Clin Appl, 2 (9): 1349-60. PMID: 21136928
  57. Riley BE, Kaiser SE, Shaler TA, Ng AC, Hara T, Hipp MS, Lage K, Xavier RJ, Ryu KY, Taguchi K, Yamamoto M, Tanaka K, Mizushima N, Komatsu M, Kopito RR (2010) ‘Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection.’ J Cell Biol, 191 (3): 537-52. PMID: 21041446
  58. D’Hertog W, Maris M, Ferreira GB, Verdrengh E, Lage K, Hansen DA, Cardozo AK, Workman CT, Moreau Y, Eizirik DL, Waelkens E, Overbergh L, Mathieu C (2010) ‘Novel insights into the global proteome responses of insulin-producing INS-1E cells to different degrees of endoplasmic reticulum stress.’ J Proteome Res, 9 (10): 5142-52. PMID: 20839851
  59. Lage K, MĂžllgĂ„rd K, Greenway S, Wakimoto H, Gorham JM, Workman CT, Bendsen E, Hansen NT, Rigina O, Roque FS, Wiese C, Christoffels VM, Roberts AE, Smoot LB, Pu WT, Donahoe PK, Tommerup N, Brunak S, Seidman CE, Seidman JG, Larsen LA (2010) ‘Dissecting spatio-temporal protein networks driving human heart development and related disorders.’ Mol Syst Biol, 6: 381. PMID: 20571530
  60. Ferreira GB, van Etten E, Lage K, Hansen DA, Moreau Y, Workman CT, Waer M, Verstuyf A, Waelkens E, Overbergh L, Mathieu C (2009) ‘Proteome analysis demonstrates profound alterations in human dendritic cell nature by TX527, an analogue of vitamin D.’ Proteomics, 9 (14): 3752-64. PMID: 19639594
  61. Bergholdt R, Brorsson C, Lage K, Nielsen JH, Brunak S, Pociot F (2009) ‘Expression profiling of human genetic and protein interaction networks in type 1 diabetes.’ PLoS One, 4 (7): e6250. PMID: 19609442
  62. Jakobsen LP, Borup R, Vestergaard J, Larsen LA, Lage K, Maroun LL, Kjaer I, Niemann CU, Andersen M, Knudsen MA, MĂžllgĂ„rd K, Tommerup N (2009) ‘Expression analyses of human cleft palate tissue suggest a role for osteopontin and immune related factors in palatal development.’ Exp Mol Med, 41 (2): 77-85. PMID: 19287188
  63. Donahoe PK, Noonan KM, Lage K (2009) ‘Genetic tools and algorithms for gene discovery in major congenital anomalies.’ Birth Defects Res A Clin Mol Teratol, 85 (1): 6-12. PMID: 19107955
  64. Lage K, Hansen NT, Karlberg EO, Eklund AC, Roque FS, Donahoe PK, Szallasi Z, Jensen TS, Brunak S (2008) ‘A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes.’ Proc Natl Acad Sci U S A, 105 (52): 20870-5. PMID: 19104045
  65. Bergholdt R, StĂžrling ZM, Lage K, Karlberg EO, Olason PI, Aalund M, Nerup J, Brunak S, Workman CT, Pociot F (2007) ‘Integrative analysis for finding genes and networks involved in diabetes and other complex diseases.’ Genome Biol, 8 (11): R253. PMID: 18045462
  66. D’Hertog W, Overbergh L, Lage K, Ferreira GB, Maris M, Gysemans C, Flamez D, Cardozo AK, Van den Bergh G, Schoofs L, Arckens L, Moreau Y, Hansen DA, Eizirik DL, Waelkens E, Mathieu C (2007) ‘Proteomics analysis of cytokine-induced dysfunction and death in insulin-producing INS-1E cells: new insights into the pathways involved.’ Mol Cell Proteomics, 6 (12): 2180-99. PMID: 17921177
  67. Sanggaard KM, Rendtorff ND, Kjaer KW, Eiberg H, Johnsen T, Gimsing S, Dyrmose J, Nielsen KO, Lage K, Tranebjaerg L (2007) ‘Branchio-oto-renal syndrome: detection of EYA1 and SIX1 mutations in five out of six Danish families by combining linkage, MLPA and sequencing analyses.’ Eur J Hum Genet, 15 (11): 1121-31. PMID: 17637804 
  68. Lage K, Karlberg EO, StĂžrling ZM, Olason PI, Pedersen AG, Rigina O, Hinsby AM, TĂŒmer Z, Pociot F, Tommerup N, Moreau Y, Brunak S (2007) ‘A human phenome-interactome network of protein complexes implicated in genetic disorders.’ Nat Biotechnol, 25 (3): 309-16. PMID: 17344885
  69. Hinsby AM, Kiemer L, Karlberg EO, Lage K, FausbĂžll A, Juncker AS, Andersen JS, Mann M, Brunak S (2006) ‘A wiring of the human nucleolus.’ Mol Cell, 22 (2): 285-95. PMID: 16630896