The Lage Lab uses genomic and computational approaches to gain mechanistic insights into diseases of major public health significance in order to lay the foundation for rationally designed medicines. This is achieved through generating cell-type-specific, multi-omic datasets, developing computational technologies to analyze them, and performing functional follow-up assays to elucidate the mechanisms that are perturbed in complex disorders such as metabolic diseases, psychiatric disorders, and cancers. The developed tools and data are made available to the scientific community in a bid to accelerate the understanding and treatment of complex diseases.
Recent News
- CAD PPI paper published in Communications Biology Jan 22, 2024
- Schizophrenia PPI paper published in iScience May 8, 2023
- ASD PPI paper published in Cell Genomics Jan 24, 2023
- Greta presents the BINe projects at WCPG 2021 Oct 14, 2021
- Preprints on using brain cell-type-specific protein interactomes to study psychiatric disorders Oct 12, 2021
- Kasper is the managing director of the new Novo Nordisk Foundation Center for Genomic Mechanisms of Disease at Broad Institute Sep 15, 2021
- We are hiring! Sep 10, 2021
- Polygenic risk score paper published in Nature Communications Sep 6, 2021
- Coexpression network paper published in Nature Neuroscience Jul 22, 2021
- Good luck at UCLA, Jacqueline Martin! Jun 24, 2021